Laser-Induced Fluorescence (LIF) Detection System

Welcome to the realm of pathogen detection. At the heart of our endeavor lies a visionary aspiration: the creation of a portable, point-of-care device capable of on-site pathogen detection. Here I am showcasing our Laser-Induced Fluorescence (LIF) Detection System prototypes and software.

Hardware Innovations

Minimal LIF Setup

Here is the humble beginnings — a minimal LIF setup built from off-the-shelf parts. Note the CPS1 battery pack provides portability:

Advanced LIF System

Here is an improved LIF system. Multiple lasers are built on a manual wheel, coupled with an automatic filter wheel controlled by the data acquisition program:

A closer look reveals some details:

Software Mastery

Our software was written in VB.net. Here is a screenshot of the main GUI of the software:

The combination of the laser and the fluorescence wavelength (called channel) could be easily selected:

Empowering Connectivity

We also created a LIF prototype with the capability to interface with smartphones. A webpage-based interface enables a smartphone to control the laser activation and data retrieval:

Here are the screenshots of the app on a smartphone.